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In contrast to EAE where the primary stimulus is immune upregulation in the presence of extrinsic myelin antigens, the CAE model illustrates that MS-like pathology can also be generated by an upstream intrinsic myelin injury, releasing antigens which secondarily trigger white matter inflammation in an immune-predisposed host

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A systematic review of 12 clinical trials on PRP injections for hair loss found that 84% of studies reported significant improvements in hair density and thickness for both men and women , highlighting its effectiveness as a non-surgical hair regrowth solution

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